Effect of cadmium injury on growth and migration of cultured human vascular endothelial cells.

@article{Kishimoto1996EffectOC,
  title={Effect of cadmium injury on growth and migration of cultured human vascular endothelial cells.},
  author={Takuji Kishimoto and Tetsuhisa Oguri and S Yamabe and Manabu Tada},
  journal={Human cell},
  year={1996},
  volume={9 1},
  pages={43-8}
}
The effect of cadmium chloride (CdCl2) on the cell proliferation and migration of cultured human umbilical vein endothelial cells (HUVECs) was quantitatively analyzed. The HUVEC viable cell count decreased dose-dependently after exposure to Cd (cadmium chloride, 10 nM-1 mM). Morphologic examination by phase-contrast microscopy revealed severe damaging effects of Cd at higher concentrations. The cytotoxic effect of Cd (10 microM-1 mM) on DNA synthesis was also concentration-dependent. When the… CONTINUE READING

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