Effect of bunazosin on cardiac sympathetic nerve activity in anesthetized rats.

@article{Yoshioka1989EffectOB,
  title={Effect of bunazosin on cardiac sympathetic nerve activity in anesthetized rats.},
  author={Mitsuhiro Yoshioka and Hiroko Togashi and Machiko Matsumoto and Masaru Minami and Hideya Saito},
  journal={Clinical and experimental hypertension. Part A, Theory and practice},
  year={1989},
  volume={11 1},
  pages={137-47}
}
The present study was undertaken to elucidate the effect of selective alpha-1 adrenoceptor antagonist, bunazosin, on sympathetic nerve activity in anesthetized rats. Intravenous administration of bunazosin (10 micrograms/kg) produced a reduction of mean arterial pressure with a significant decrease in heart rate. Accompanied with its hypotension and… CONTINUE READING