Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.

@article{Lek2008EffectOB,
  title={Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.},
  author={Rixt F. Riemersma-van der Lek and Dick F. Swaab and Jos W. R. Twisk and Elly M. Hol and Witte J. G. Hoogendijk and Eus. J. W. Van Someren},
  journal={JAMA},
  year={2008},
  volume={299 22},
  pages={
          2642-55
        }
}
CONTEXT Cognitive decline, mood, behavioral and sleep disturbances, and limitations of activities of daily living commonly burden elderly patients with dementia and their caregivers. Circadian rhythm disturbances have been associated with these symptoms. OBJECTIVE To determine whether the progression of cognitive and noncognitive symptoms may be ameliorated by individual or combined long-term application of the 2 major synchronizers of the circadian timing system: bright light and melatonin… CONTINUE READING
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