Effect of bitter tastants on human bronchi

  title={Effect of bitter tastants on human bronchi},
  author={Alyn H. Morice and Robert T Bennett and Mubarak A. Chaudhry and Michael Edward Cowen and Steven C. Griffin and Mahmoud Loubani},
  journal={Nature Medicine},
To the Editor: We read with interest the report of the effects of bitter tastants on airway smooth muscle by Deshpande et al.1 and the related News and Views article by Sanderson and Madison2. Deshpande et al.1 report a previously undescribed modulator of airway tone with a unique mode of relaxation in airway smooth muscle that may prove to be clinically significant. We attempted to reproduce the data presented using second-order human bronchi obtained from people with lung cancer after… CONTINUE READING