Effect of biopassive and bioactive surface-coatings on the hemocompatibility of membrane oxygenators.

@article{Zimmermann2007EffectOB,
  title={Effect of biopassive and bioactive surface-coatings on the hemocompatibility of membrane oxygenators.},
  author={Anja Kerstin Zimmermann and Norbert Weber and Hermann Aebert and Gerhard Ziemer and Hans P. Wendel},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  year={2007},
  volume={80 2},
  pages={433-9}
}
Postoperative complications associated with cardiopulmonary bypass (CPB) surgery and extracorporeal circulation (ECC) procedures are still a major clinical issue. Improving the hemocompatibility of blood contacting devices used for ECC procedures may ameliorate various postpump syndromes. In a simulated CPB model using human blood, we investigated the hemocompatibility, fibrinogen adsorption, and platelet receptor (GPIIb-IIIa) binding capacity of surface-modified membrane oxygenators (Jostra… CONTINUE READING
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