Effect of biological implant surface coatings on bone formation, applying collagen, proteoglycans, glycosaminoglycans and growth factors.

@article{Stadlinger2008EffectOB,
  title={Effect of biological implant surface coatings on bone formation, applying collagen, proteoglycans, glycosaminoglycans and growth factors.},
  author={Bernd Stadlinger and Eckart Pilling and Ronald Mai and Susanne Bierbaum and Ricardo Berhardt and Dieter Scharnweber and Uwe Eckelt},
  journal={Journal of materials science. Materials in medicine},
  year={2008},
  volume={19 3},
  pages={1043-9}
}
OBJECTIVES The aim of the present study was to evaluate six different implant surface coatings with respect to bone formation. Being major structural components of the extracellular matrix, collagen, the non-collagenous components decorin/chondroitin sulphate (CS) and the growth factors TGF-beta1/BMP-4 served in different combinations as coatings of experimental titanium implants. MATERIALS AND METHODS Eight miniature pigs received each six implants in the mandible. The implant design showed… CONTINUE READING
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