Effect of bilateral carotid body resection on the counterregulatory response to hypoglycaemia in humans.

@article{Wehrwein2015EffectOB,
  title={Effect of bilateral carotid body resection on the counterregulatory response to hypoglycaemia in humans.},
  author={Erica A. Wehrwein and Jacqueline K. Limberg and Jennifer L. Taylor and Simmi Dube and Ananda Basu and Rita Basu and Robert A. Rizza and Timothy B. Curry and Michael Joseph Joyner},
  journal={Experimental physiology},
  year={2015},
  volume={100 1},
  pages={
          69-78
        }
}
NEW FINDINGS What is the central question of this study? Hyperoxia blunts hypoglycaemia counterregulation in healthy adults. We hypothesized that this effect is mediated by the carotid bodies and that: (i) hyperoxia would have no effect on hypoglycaemia counterregulation in carotid body-resected patients; and (ii) carotid body-resected patients would exhibit an impaired counterregulatory response to hypoglycaemia. What is the main finding and its importance? Our data indicate that the effect of… CONTINUE READING
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