Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients.

@article{Tenenbaum2005EffectOB,
  title={Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients.},
  author={Alexander Tenenbaum and Michael Motro and Enrique Z Fisman and Y. Adler and Joseph Shemesh and David Tann{\'e} and Jonathan Leor and Valentina Boyko and Ehud E Schwammenthal and Solomon M Behar},
  journal={European heart journal},
  year={2005},
  volume={26 19},
  pages={2032-8}
}
AIMS To assess the effect of fibric acid derivative bezafibrate on incidence of type 2 diabetes in obese patients over a median 6.3 years follow-up period. METHODS AND RESULTS The study sample comprised 339 non-diabetic obese patients (body mass index > or = 30.0 kg/m2) aged 42-74. Patients received either bezafibrate retard 400 mg (178 patients) or placebo (161 patients) once daily. Development of new diabetes was recorded in 98 patients: in 56 (37.0%) from the placebo group vs. 42 (27.1… CONTINUE READING
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