Effect of beta-hydroxy-beta-methylbutyrate on protein metabolism in bed-ridden elderly receiving tube feeding.
@article{Hsieh2010EffectOB, title={Effect of beta-hydroxy-beta-methylbutyrate on protein metabolism in bed-ridden elderly receiving tube feeding.}, author={Lan-Chi Hsieh and Chau Jen Chow and W. C. Chang and Tsung-Han Liu and Chen-Kang Chang}, journal={Asia Pacific journal of clinical nutrition}, year={2010}, volume={19 2}, pages={ 200-8 } }
Malnutrition and muscle loss are common in bed-ridden elderly nursing home residents. Supplementation of beta-hydroxy-beta-methylbutyrate (HMB) has been shown to prevent muscle loss in several catabolic conditions. The aim of this study was to investigate the effect of HMB supplementation on body composition and protein metabolism in bed-ridden elderly nursing home residents receiving tube feeding. The subjects were randomly assigned to HMB (n=39, 2 g/d) or control group (n=40). Anthropometry…
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The findings raise a problem concerning nutritional management of bed-ridden patients, as the incidence of protein-malnutrition, as evidenced by decreased arm muscle circumference and hypoalbuminemia, in the patients with tube feeding was significantly higher than that in the healthy elders.
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