Effect of benzo[a]pyrene on sister-chromatid exchange in fetal hamster liver exposed in utero.

Abstract

Benzo[a]pyrene between 50 and 125 mg/kg administered maternally caused a dose-related increase in sister-chromatid exchange in fetal hamster liver cells. There was no difference on days 11, 13 and 15 of gestation in the sensitivity of fetal liver to benzo[a]pyrene. 

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