Effect of baseline renal function on tenofovir-containing antiretroviral therapy outcomes in Zambia.

@article{Mulenga2014EffectOB,
  title={Effect of baseline renal function on tenofovir-containing antiretroviral therapy outcomes in Zambia.},
  author={Lloyd B. Mulenga and Patrick Musonda and Albert J. Mwango and Michael J. Vinikoor and Mary-Ann Davies and Aggrey Mweemba and Alexandra Calmy and Jeffrey S. A. Stringer and O Keiser and Benjamin H Chi and Gilles Wandeler},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2014},
  volume={58 10},
  pages={1473-80}
}
BACKGROUND Although tenofovir disoproxil fumarate (TDF) use has increased as part of first-line antiretroviral therapy (ART) across sub-Saharan Africa, renal outcomes among patients receiving TDF remain poorly understood. We assessed changes in renal function and mortality in patients starting TDF- or non-TDF-containing ART in Lusaka, Zambia. METHODS We included patients aged ≥16 years who started ART from 2007 onward, with documented baseline weight and serum creatinine. Renal dysfunction… CONTINUE READING
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