Effect of autophagy on paclitaxel-induced CaSki cell death.

@article{Sun2010EffectOA,
  title={Effect of autophagy on paclitaxel-induced CaSki cell death.},
  author={Yang Sun and Long Jin and Jiahua Liu and Saimei Lin and Yin Yang and Yuxia Sui and Hong Fei Shi},
  journal={Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences},
  year={2010},
  volume={35 6},
  pages={
          557-65
        }
}
OBJECTIVE To observe the effect of autophagy on paclitaxel-induced CaSki cell death through the regulation of the expression of autophagy gene Beclin1, and to explore the interaction and relationship between autophagy and apoptosis. METHODS Eukaryotic expression vector pcDNA3.1-Beclin1 and RNA interference vector pSUPER-Beclin1 were transfected into human cervical cancer CaSki cells in vitro and screened for stable expression cell lines. The formation of autophagic vacuoles was observed with… CONTINUE READING

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