Effect of autologous bone-marrow cell transplantation on ischemic ulcer in patients with Buerger's disease.

@article{Saito2007EffectOA,
  title={Effect of autologous bone-marrow cell transplantation on ischemic ulcer in patients with Buerger's disease.},
  author={Yutaka Saito and Ken-Ichiro Sasaki and Yousuke Katsuda and Toyoaki Murohara and Yoshiaki Takeshita and Teiji Okazaki and Ken Arima and Yoshio Katsuki and Satoshi Shintani and Toshifumi Shimada and Hidetoshi Akashi and Hisao Ikeda and Tsutomu Imaizumi},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2007},
  volume={71 8},
  pages={1187-92}
}
BACKGROUND Thromboangiitis obliterans, also known as Buerger's disease, is characterized by peripheral occlusive changes in the arteries of the upper and lower limbs and treatment is often ineffective. Intramuscular transplantation of autologous bone marrow-mononuclear cells (BM-MNC) has been recently reported as improving the symptoms and clinical manifestations in patients with severely ischemic limbs, mostly caused by arteriosclerosis obliterans. The present study focused on the patients… CONTINUE READING

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