Effect of ascorbic acid prophylaxis on the frequency of chromosome aberrations in the peripheral lymphocytes of coal-tar workers.


The possible anti-mutagenic potential of prophylactically administered ascorbic acid (AA) preparations was studied in a group of 35 coal-tar workers occupationally exposed to PAH and benzene. The effectiveness of AA prophylaxis was assessed by differences in the frequency of chromosome aberrations in peripheral blood lymphocytes of the exposed workers… (More)


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