Effect of ascorbic acid on guinea pig adrenal adenylate cyclase activity and plasma cortisol.

@article{Doulas1987EffectOA,
  title={Effect of ascorbic acid on guinea pig adrenal adenylate cyclase activity and plasma cortisol.},
  author={N L Doulas and Andreas Constantopoulos and B I Litsios},
  journal={The Journal of nutrition},
  year={1987},
  volume={117 6},
  pages={1108-14}
}
Intra-adrenal ascorbic acid (AsA) concentrations exert a braking or modulating effect upon steroid release. Because changes in steroidogenesis are mediated through alterations in adenylate cyclase activity (ACL), the effect of varied AsA plasma concentrations on guinea pig adrenal ACL activity and plasma cortisol was studied. Forty-two male guinea pigs were randomly allocated to the following seven groups: controls, scorbutic, and groups given 0.1, 5, 10, 20 or 100 mg ascorbic acid/100 g body… CONTINUE READING

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