Effect of arsenic trioxide on human hepatoma cell line BEL-7402 cultured in vitro.

@article{Xu2000EffectOA,
  title={Effect of arsenic trioxide on human hepatoma cell line BEL-7402 cultured in vitro.},
  author={Hong-yu Xu and You-lin Yang and Yuan-yuan Gao and Qiao- Li Wu and Guang-Qiang Gao},
  journal={World journal of gastroenterology},
  year={2000},
  volume={6 5},
  pages={681-687}
}
AIM:To study the effect of a varying concentrations of arsenic trioxide on human hepatoma cell line BEL-7402 cultured in vitro and its mechanism of action.METHODS:The BEL-7402 cells were treated with arsenic trioxide (at the concentrations of 0.5 1 2&mgr;mol/L, respectively) for 4 successive days. The cell growth and proliferation were observed by cell counting and cell-growth curve. Morphologic changes were studied with electronmicroscopy. Flow cytometry was used to assay cell-DNA distribution… CONTINUE READING