Effect of antisense RNA targeting polo-like kinase 1 on cell cycle and proliferation in A549 cells.

@article{Zhou2004EffectOA,
  title={Effect of antisense RNA targeting polo-like kinase 1 on cell cycle and proliferation in A549 cells.},
  author={Qiong Zhou and Ming Bai and Yuan Su},
  journal={Chinese medical journal},
  year={2004},
  volume={117 11},
  pages={1642-9}
}
BACKGROUND Expression of polo-like kinase 1 (Plk1) is elevated in lung cancer and has been proposed as having prognostic value and related to resistance to chemotherapy and radiation. In addition, Plk1 has several functions in mitotic progression. In this study, the authors investigated the effect of Plk1 depletion on cell cycle progression and… CONTINUE READING