Effect of antipsychotic replacement with quetiapine on the symptoms and quality of life of schizophrenic patients with extrapyramidal symptoms.

@article{Taniguchi2006EffectOA,
  title={Effect of antipsychotic replacement with quetiapine on the symptoms and quality of life of schizophrenic patients with extrapyramidal symptoms.},
  author={Takahide Taniguchi and Satsuki Sumitani and Michitaka Aono and Junichi Ichi Iga and Sawako Kinouchi and Hirosi Aki and Mami Matsushita and Kyoko Taniguchi and Mami Tsuno and Kazunari Yamanishi and Masahito Tomotake and Yasuhiro Kaneda and Tetsuro Ohmori},
  journal={Human psychopharmacology},
  year={2006},
  volume={21 7},
  pages={439-45}
}
Replacement of antipsychotic drugs with quetiapine (QTP) was tried in a naturalistic setting in chronic schizophrenic patients who still showed moderate psychiatric symptoms and either showed extrapyramidal symptoms (EPS) or took anti-parkinson drugs for the EPS. QTP was added on and gradually increased while the previous drugs were tapered and discontinued whenever possible. Clinical symptoms, objective and subjective QOL, and EPS were measured before and 6 months after QTP addition, using… CONTINUE READING

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