Effect of antihypertensive therapy on lysine incorporation into vascular protein of the spontaneously hypertensive rat.

@article{Yamori1976EffectOA,
  title={Effect of antihypertensive therapy on lysine incorporation into vascular protein of the spontaneously hypertensive rat.},
  author={Yukio Yamori and Teruhiro Nakada and Walter Lovenberg},
  journal={European journal of pharmacology},
  year={1976},
  volume={38 2},
  pages={349-55}
}
Young spontaneously hypertensive rats (SHR) were either treated with hydralazine or hexamethonium or splanchnicotomized, so that the development of hypertension was effectively arrested for two weeks. The rate of incorporation of 3H-lysine into non-collagenous proteins in vivo of the heart, aorta and mesenteric arteries was determined in the treated SHR, as well as control SHR and normal Wistar/Kyoto (WK) rats. The lysine incorporation into the non-collagenous protein of mesenteric arteries was… CONTINUE READING