Effect of antidepressants on neurotransmitter reuptake by synaptosomes of control and stressed rats

@article{Nikuradze2004EffectOA,
  title={Effect of antidepressants on neurotransmitter reuptake by synaptosomes of control and stressed rats},
  author={V. A. Nikuradze and Nicolai A. Avdulov and Academician A. V. Val'dman},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2004},
  volume={105},
  pages={358-360}
}
An important role in the mechanism of action of antidepressants is ascribed to their ability to inhibit neurotransmitter reuptake by synaptosomes [ii, 15], for it has been suggested that the monoamine level in the synaptic cleft is lowered in depressions [16]. Investigations of this kind have usually been undertaken on synaptosomes, isolated from the brain… CONTINUE READING