Effect of antidepressants on brain-derived neurotrophic factor (BDNF) release from platelets in the rats.

@article{Watanabe2010EffectOA,
  title={Effect of antidepressants on brain-derived neurotrophic factor (BDNF) release from platelets in the rats.},
  author={Kimihiko Watanabe and Eri Hashimoto and Wataru Ukai and Takao Ishii and Toshihiro Yoshinaga and Takafumi Ono and Masaru Tateno and Ippei Watanabe and Tomohiro Shirasaka and Satoshi Saito and Toshikazu Saito},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={2010},
  volume={34 8},
  pages={1450-4}
}
Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family, and enhances the growth and maintenance of several neuronal systems. In addition, BDNF may promote neurogenesis and protect against hippocampal volume loss in depressive disorders. Although first detected in brain, BDNF also exists in peripheral tissues and is mainly stored in platelets and circulates in blood. Recent reports indicate that serum BDNF levels in depressive patients are lower than in control subjects, and… CONTINUE READING