Effect of anti-haemagglutinin-esterase glycoprotein monoclonal antibodies on the receptor-destroying activity of influenza C virus.

Five monoclonal antibodies (J14, J9, Q5, K16, S16), directed to three distinct antigenic sites (A-1, A-2, B-1) on the haemagglutinin-esterase glycoprotein of influenza C virus, were analysed for their ability to inhibit the receptor-destroying enzyme (RDE) activity of the virus, utilizing various assay systems. The ability of influenza C virus to destroy… (More)