Effect of antenatal tetrandrine administration on endothelin-1 and epidermal growth factor levels in the lungs of rats with experimental diaphragmatic hernia.

Abstract

PURPOSE The aim of this study was to evaluate the effect of the traditional Chinese medicine tetrandrine (Tet) and to determine its possible mechanism on expression of endothelin-1 (ET-1) and epidermal growth factor (EGF) in the lung of a rat model of nitrofen-induced congenital diaphragmatic hernia (CDH). METHODS A single oral dose (115 mg/kg) of… (More)

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@article{Lin2007EffectOA, title={Effect of antenatal tetrandrine administration on endothelin-1 and epidermal growth factor levels in the lungs of rats with experimental diaphragmatic hernia.}, author={Han Lin and Yonggang Wang and Zhongxun Xiong and Yunman Tang and Wenying Liu}, journal={Journal of pediatric surgery}, year={2007}, volume={42 10}, pages={1644-51} }