Effect of angiotensin-converting enzyme inhibition with perindopril and beta-blockade with atenolol on retinal blood flow in hypertensive diabetic subjects.

@article{Patel1998EffectOA,
  title={Effect of angiotensin-converting enzyme inhibition with perindopril and beta-blockade with atenolol on retinal blood flow in hypertensive diabetic subjects.},
  author={Vinod G Patel and Salwan M Rassam and H Cheng Chen and M. T. Islwyn Jones and Eva Maria Kohner},
  journal={Metabolism: clinical and experimental},
  year={1998},
  volume={47 12 Suppl 1},
  pages={28-33}
}
The effect of angiotensin-converting enzyme (ACE) inhibitors on the diabetic retinal circulation has not been studied previously. The aim of this study was to evaluate the effect of ACE inhibition and beta-blockade on retinal blood flow (RBF) in a group of 45 hypertensive diabetic subjects using a randomized double-blind trial over a period of 12 months. Laser Doppler velocimetry and computed image analysis were used to measure RBF. The changes in blood pressure over 12 months were comparable… CONTINUE READING

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