Effect of anemia and renal cytokine production on erythropoietin production during blood-stage malaria.

@article{Chang2004EffectOA,
  title={Effect of anemia and renal cytokine production on erythropoietin production during blood-stage malaria.},
  author={Kai-Hsin Chang and Mary M Stevenson},
  journal={Kidney international},
  year={2004},
  volume={65 5},
  pages={1640-6}
}
BACKGROUND Renal dysfunction and severe anemia are clinical complications of blood-stage malaria. Erythropoietin (Epo) is a hormone produced by the kidney and plays an essential role in stimulating erythrocyte production. Renal dysfunction in malaria is associated with changes in renal cytokine levels, which may affect the production of Epo and the alleviation of anemia. METHODS Resistant C57BL/6 (B6) and susceptible A/J mice were infected with Plasmodium chabaudi AS. The levels of Epo and… CONTINUE READING

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