Effect of an extract based on the medicinal mushroom Agaricus blazei murill on release of cytokines, chemokines and leukocyte growth factors in human blood ex vivo and in vivo.

@article{Johnson2009EffectOA,
  title={Effect of an extract based on the medicinal mushroom Agaricus blazei murill on release of cytokines, chemokines and leukocyte growth factors in human blood ex vivo and in vivo.},
  author={Egil Johnson and Dag Tidemann F\orland and L Saetre and Soosaipillai V Bernardshaw and Torstein Lyberg and Geir Hetland},
  journal={Scandinavian journal of immunology},
  year={2009},
  volume={69 3},
  pages={242-50}
}
An immunostimulatory extract based on the medicinal mushroom Agaricus blazei Murill (AbM) has been shown to stimulate mononuclear phagocytes in vitro to produce pro-inflammatory cytokines, and to protect against lethal peritonitis in mice. The present aim was to study the effect of AbM on release of several cytokines in human whole blood both after stimulation ex vivo and in vivo after oral intake over several days in healthy volunteers. The 17 signal substances examined were; T helper 1 (Th1… CONTINUE READING
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