Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study

@article{Polosa2011EffectOA,
  title={Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study},
  author={Riccardo Polosa and Pasquale Caponnetto and Jaymin B Morjaria and Gabriella A. Papale and D. Campagna and Cristina Russo},
  journal={BMC Public Health},
  year={2011},
  volume={11},
  pages={786 - 786}
}
BackgroundCigarette smoking is a tough addiction to break. Therefore, improved approaches to smoking cessation are necessary. The electronic-cigarette (e-Cigarette), a battery-powered electronic nicotine delivery device (ENDD) resembling a cigarette, may help smokers to remain abstinent during their quit attempt or to reduce cigarette consumption. Efficacy and safety of these devices in long-term smoking cessation and/or smoking reduction studies have never been investigated.MethodsIn this… Expand
Electronic Cigarettes Efficacy and Safety at 12 Months: Cohort Study
TLDR
If e-cigarette safety will be confirmed, however, the use of e-cigarettes alone may facilitate quitters remaining so, although e-smokers showed a minimal but significantly higher increase in self-rated health than other smokers. Expand
EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as Tobacco Cigarettes Substitute: A Prospective 12-Month Randomized Control Design Study
TLDR
In smokers not intending to quit, the use of e-cigarettes, with or without nicotine, decreased cigarette consumption and elicited enduring tobacco abstinence without causing significant side effects. Expand
Effect of Electronic Cigarettes on Smoking Reduction and Cessation in Korean Male Smokers: A Randomized Controlled Study
TLDR
The effect of e-cigarette on smoking cessation was similar compared with that of nicotine gum, a well-documented NRT, and e-cigarettes were well tolerated by the study population, therefore, the use of E-cigarettes as an NRT may be considered for smoking-cessation purposes. Expand
Effectiveness and tolerability of electronic cigarette in real-life: a 24-month prospective observational study
TLDR
Long-term e-Cigarette use can substantially decrease cigarette consumption in smokers not willing to quit and is well tolerated. Expand
Acute electronic cigarette use: nicotine delivery and subjective effects in regular users
TLDR
These findings demonstrate reliable blood nicotine delivery after the acute use of this brand/model of e-cigarette in a sample of regular users, and Tobacco-related withdrawal symptoms and urge to smoke were significantly reduced. Expand
Effectiveness and tolerability of electronic cigarette in real-life: a 24-month prospective observational study
TLDR
Long-term e-Cigarette use can substantially decrease cig- arette consumption in smokers not willing to quit and is well tolerated. Expand
Cohort study of electronic cigarette use: effectiveness and safety at 24 months
TLDR
E-cigarette use alone might support tobacco quitters remaining abstinent from smoking, but dual use did not improve the likelihood of quitting tobacco or e-cigarettes, but may be helpful to reduce tobacco consumption. Expand
Benefits of e-cigarettes in smoking reduction and in pulmonary health among chronic smokers undergoing a lung cancer screening program at 6 months.
TLDR
Pulmonary health, assessed with self-reported measures, clinical evaluations and the Leicester Cough Questionnaire, improved in participants who stopped smoking compared to their own baseline and the efficacy and safety of e-cigarettes in helping smokers reducing tobacco consumption and improving pulmonary health status are added. Expand
Electronic Cigarettes-Attitudes and Use in Germany.
TLDR
The vapers were more often men, were less addicted to nicotine and had a higher motivation to stop smoking than the smokers, and vapers had a more positive attitude towards e-cigarettes and higher self-efficacy in terms of abstaining from cigarettes in certain situations. Expand
Effectiveness of the Electronic Cigarette: An Eight-Week Flemish Study with Six-Month Follow-up on Smoking Reduction, Craving and Experienced Benefits and Complaints
TLDR
In a series of controlled lab sessions with e-cig naïve tobacco smokers, second generation e-cigs were shown to be immediately and highly effective in reducing abstinence induced cigarette craving and withdrawal symptoms, while not resulting in increases in eCO. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 53 REFERENCES
Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial
TLDR
The 16 mg Ruyan V8 ENDD alleviated desire to smoke after overnight abstinence, was well tolerated and had a pharmacokinetic profile more like the Nicorette inhalator than a tobacco cigarette. Expand
Randomised trial investigating effect of a novel nicotine delivery device (Eclipse) and a nicotine oral inhaler on smoking behaviour, nicotine and carbon monoxide exposure, and motivation to quit
TLDR
Eclipse can dramatically decrease cigarette consumption without causing withdrawal symptoms or decreases in nicotine concentrations or motivation to quit altogether, and Eclipse may not be a safer cigarette. Expand
Effect of a nicotine-free inhalator as part of a smoking-cessation programme
TLDR
The results of the logistic model analysis indicate that a high GN-SBQ score is a strong independent predictor for successful quitting at 24 weeks in the PAIPO group, and nicotine-free inhalators may be beneficial when used in the context of smoking-cessation interventions. Expand
Reduced-nicotine content cigarettes: Is there potential to aid smoking cessation?
TLDR
Three clinical trials that suggest that smokers can dissociate nicotine delivery from the act of smoking if they use reduced-nicotine content cigarettes in combination with nicotine replacement therapy are identified. Expand
Efficacy of the nicotine inhaler in smoking reduction: A double-blind, randomized trial.
TLDR
The nicotine inhaler can help smokers who are unable or unwilling to quit to reduce daily cigarette consumption, which may be a health benefit on its own and may further promote quitting. Expand
Effects of cigarette reduction on cardiovascular risk factors and subjective measures.
TLDR
The results show the availability of reliable and dose-sensitive biomarkers and that reduction in smoking can lead to significant but only modest changes in cardiovascular risk factors in healthy smokers. Expand
A Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects
TLDR
Under these acute testing conditions, neither of the electronic cigarettes exposed users to measurable levels of nicotine or CO, although both suppressed nicotine/tobacco abstinence symptom ratings and increased product acceptability ratings. Expand
Electronic cigarettes: a survey of users
TLDR
Ecigarettes were used mainly to quit smoking, and may be helpful for this purpose, but several respondents were concerned about potential toxicity. Expand
Smoking reduction promotes smoking cessation: results from a double blind, randomized, placebo-controlled trial of nicotine gum with 2-year follow-up.
TLDR
Nicotine gum promoted cessation in this population of smokers unwilling to quit, with a linear relationship between decrease in number of daily cigarettes and decrease in plasma cotinine, exhaled carbon monoxide and plasma thiocyanate. Expand
Smoking reduction with oral nicotine inhalers: double blind, randomised clinical trial of efficacy and safety
TLDR
Nicotine inhalers effectively and safely achieved sustained reduction in smoking over 24 months and reduction with or without nicotine substitution may be a feasible first step towards smoking cessation in people not able or not willing to stop abruptly. Expand
...
1
2
3
4
5
...