Effect of an activated charcoal product (DOAC Stop™) intended for extracting DOACs on various other APTT-prolonging anticoagulants

  title={Effect of an activated charcoal product (DOAC Stop™) intended for extracting DOACs on various other APTT-prolonging anticoagulants},
  author={T. Exner and M. Ahuja and Lisa Ellwood},
  journal={Clinical Chemistry and Laboratory Medicine (CCLM)},
  pages={690 - 696}
  • T. Exner, M. Ahuja, Lisa Ellwood
  • Published 2019
  • Medicine
  • Clinical Chemistry and Laboratory Medicine (CCLM)
  • Abstract Background The aim of the study was to investigate the specificity of an activated charcoal-based product (DOAC Stop™) initially intended for the specific extraction of direct oral anticoagulants (DOACs) from test plasmas on a range of other anticoagulants. Methods Test plasmas were prepared by adding various anticoagulants to pooled normal plasma at concentrations prolonging an activated partial thromboplastin time (APTT) test by a factor of 1.5–3. These plasmas were treated with DOAC… CONTINUE READING
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