Effect of an Inorganic and Organic Form of Dietary Selenium on the Promotional Stage of Mammary Carcinogenesis in the Rat 1

The relative effectiveness of either sodium selenite or selenomethionine in the inhibition of mammary carcinogenesis was studied in virgin female Sprague-Dawley rats. In one experiment, rats were given 50 mg of 1-methyl-1-nitrosourea per kg of body weight s.c. at 50 days of age. Beginning 7 days post-1 -methyl1-nitrosourea, they were assigned to a basal… CONTINUE READING