Effect of an “Atherogenic” Diet containing Starch or Sucrose on the Blood Lipids of Young Men

@article{Akinyanju1968EffectOA,
  title={Effect of an “Atherogenic” Diet containing Starch or Sucrose on the Blood Lipids of Young Men},
  author={P. A. Akinyanju and R. U. Qureshi and A. J. Salter and John S. Yudkin},
  journal={Nature},
  year={1968},
  volume={218},
  pages={975-977}
}
YUDKIN has suggested that the dietary change most likely to be an aetiological factor in ischaemic heart disease is the replacement of a large proportion of starch by sucrose1. It is thus relevant to investigate the differences that can be caused experimentally when starch or sugar is the principal dietary carbohydrate. We report here studies on human volunteers. 
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The percentage of total daily energy provided by fat, carbohydrate and protein remained constant, but the nature of thefat and carbohydrate was altered, and the quantity of sucrose was increased at the expense of complex carbohydrate. Expand
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Different effects of sucrose, glucose, fructose, and starch on serum lipid levels in patients with C-HTG are demonstrated, and their relation to those in normal subjects is discussed. Expand
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It is suggested that only some individuals are susceptible to the development of ischaemic heart disease by dietary sucrose, and that these may be identified as those that show ‘sucrose-induced hyperinsulinism’. Expand
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The results indicate that the consumption of sucrose can increase blood lipids that are considered to be risk factors in heart disease and that males and carbohydrate-sensitive individuals may be more susceptible than others to the effects of Sucrose. Expand
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The studies reported in Part 2 and 3 of this series of papers indicate that sucrose in comparison with starch is uniformly hyperlipidemic in diets having large amounts of saturated fat and cholesterol. Expand
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It is suggested that there is a synergistic effect between dietary sucrose and animal fat in hyperlipoproteinemic patients fed formula diets which simulated a typical North American diet for two 28-day periods. Expand
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The present review adresses the question whether simple and complex carbohydrates may result in different physiological responses with emphasis on glucose tolerance, human energy metabolism, andExpand
Fructose as sweetening agent in normal and diabetic nutrition
  • V. Marks
  • Medicine
  • Acta diabetologia latina
  • 2005
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The desire to eat sweet things is highly developed in man, and in some individuals it becomes a compulsion verging on « craving » which can be defined as a morbid compulsion, an important consequence of satisfying the desire for sweetness is obesity. Expand
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