Effect of an α1-adrenergic blocker on plasticity elicited by motor training

Recovery of motor function elicited by motor training after cortical lesions in rats is enhanced by norepinephrine (neurotransmitter mediating α1-adrenergic function) and downregulated by α1-adrenergic antagonists. In spite of this, α1-adrenergic antagonists are used to treat elderly patients with hypertension and prostate hyperplasia in stroke settings… CONTINUE READING