Effect of amphotericin B and fluconazole on platelet membrane glycoproteins.

Abstract

BACKGROUND Fever, chills, and reduced platelet recovery may result when platelets are transfused simultaneously with amphotericin B. Amphotericin B reportedly increases the pitting of membranes in stored platelets. STUDY DESIGN AND METHODS The effects of amphotericin B and another antifungal agent, fluconazole, on platelet membrane glycoproteins (GP) were… (More)

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