Effect of amount and types of dietary fat on intestinal bacterial 7α-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during different stages of colon tumor promotion

@inproceedings{Reddy1996EffectOA,
  title={Effect of amount and types of dietary fat on intestinal bacterial 7α-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during different stages of colon tumor promotion},
  author={B Siva Sankar Reddy and Barbara Simi and Neha Patel and C{\'e}sar Manrique Aliaga and Chinthalapally V. Rao},
  year={1996}
}
Abstract It is evident from many studies that the effect of dietary fat on colon tumor promotion depends not only on the amount of fat but especially on fatty acid composition. Animal model studies have shown that diets which are high in omega-6 fatty acids increase colon tumor promotion, whereas diets rich in omega-3 fatty acids have no such enhancing effect. The mechanisms by which the high fat content of the diet promotes colon carcinogenesis may include the production of secondary bile… CONTINUE READING

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