Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators.

@article{Pitt2000EffectOA,
  title={Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators.},
  author={Bertram C Pitt and Robert P. Byington and Curt D. Furberg and Donald B. Hunninghake and G. B. John Mancini and Marilyn E Miller and Ward Riley},
  journal={Circulation},
  year={2000},
  volume={102 13},
  pages={1503-10}
}
BACKGROUND The results of angiographic studies have suggested that calcium channel-blocking agents may prevent new coronary lesion formation, the progression of minimal lesions, or both. METHODS AND RESULTS The Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) was a multicenter, randomized, placebo-controlled, double-masked clinical trial designed to test whether amlodipine would slow the progression of early coronary atherosclerosis in 825 patients with… CONTINUE READING

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