Effect of amiloride on electrolyte transport parameters of the main duct of the rabbit mandibular salivary gland

@article{Bijman1983EffectOA,
  title={Effect of amiloride on electrolyte transport parameters of the main duct of the rabbit mandibular salivary gland},
  author={J. T. Bijman and David I. Cook and C. H. van Os},
  journal={Pfl{\"u}gers Archiv},
  year={1983},
  volume={398},
  pages={96-102}
}
We have studied the response of the rabbit mandibular main duct perfused in vitro to luminally administered amiloride. The half-maximal inhibitory concentrations (KI) when the duct was bathed in Cl solutions were: for net Na+ transport, 3×10−6 mol l−1; for transepithelial potential difference, 6×10−6 mol l−1; and for transepithelial conductance, 3×10−7 mol l−1. Substitution of the impermeant SO 4 2− anion for Cl− changed the KI for conductance to 3×10−6 mol l−1. Within Cl−-containing media, the… CONTINUE READING
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References

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Showing 1-10 of 27 references

Temperature dependence of transepithelial potential in isolated rabbit mandibular main duct

  • J Bijman, CH Van Os
  • 1982

The action of amiloride on the rabbit mandibular duct perfused in vitro

  • DI Cook, J Bijman, CH Van Os
  • 1982
1 Excerpt

Mechanism for HCO~ stimulation of NaC1 reabsorption in rabbit submaxillary main duct epithelium

  • J Bijman, JFG Slegers, CH Van Os
  • 1980
2 Excerpts

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