Effect of aluminum upon conditioned avoidance response acquisition in the absence of neurofibrillary degeneration.


Aluminum induces neurofibrillary degeneration in cats but not rats. Cats develop a progressive encephalopathy in which an early manifestation is impaired learning-memory performance. At brain aluminum concentrations of 5 to 6 times that found in cat, rats demonstrate an initial transient weight loss and acquisition deficit immediately following intracranial… (More)


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