Effect of altered thyroid status on in vitro cardiac performance in rats.

@article{Mcdonough1987EffectOA,
  title={Effect of altered thyroid status on in vitro cardiac performance in rats.},
  author={Kathleen H Mcdonough and Victor S Chen and John J. Spitzer},
  journal={The American journal of physiology},
  year={1987},
  volume={252 4 Pt 2},
  pages={H788-95}
}
Effect of a chronic excess or deficit of thyroid hormone on intrinsic myocardial performance in rats was assessed. Animals were thyroidectomized or treated with thyroid hormone or vehicle 6-7 wk before the study. Body weight and heart weight were decreased in the hypothyroid group, and heart weight was elevated in the hyperthyroid group. Hearts were removed from thyroidectomized, euthyroid or thyroid-treated animals and studied as isolated, perfused working heart preparations. Ventricular… CONTINUE READING
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