Effect of altered blood plasma osmolalities on regional brain amino acid concentrations and focal seizure susceptibility in the rat.

@article{Baxter1986EffectOA,
  title={Effect of altered blood plasma osmolalities on regional brain amino acid concentrations and focal seizure susceptibility in the rat.},
  author={Claude F. Baxter and Claude Guy Wasterlain and K L Hallden and S F Pruess},
  journal={Journal of neurochemistry},
  year={1986},
  volume={47 2},
  pages={617-24}
}
Blood plasma hypo- or hyperosmolality alters significantly the concentration of some amino acids in brain tissues of the medial septum and hippocampus of adult Sprague-Dawley rats. With some notable exceptions, brain amino acid concentrations decreased under hypoosmotic conditions and increased under hyperosmotic conditions. Osmotic changes and brain amino acid changes appear to be related to each other in an almost linear fashion. A comparison of rats and toads indicates that the patterns of… CONTINUE READING

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