Effect of alpha1-adrenergic stimulation of Cl- secretion and signal transduction in exocrine glands (Rana esculenta).

@article{Gudme2000EffectOA,
  title={Effect of alpha1-adrenergic stimulation of Cl- secretion and signal transduction in exocrine glands (Rana esculenta).},
  author={Charlotte Nini Gudme and Morten Schak Nielsen and Robert R. Nielsen},
  journal={Acta physiologica Scandinavica},
  year={2000},
  volume={169 2},
  pages={173-82}
}
In the present work, the effect of stimulation of alpha-adrenergic receptors on Cl- secretion via exocrine frog skin glands was investigated. The alpha-adrenergic stimulation was performed by addition of the adrenergic agonist noradrenaline in the presence of the beta-adrenergic antagonist propranolol. In the presence of propranolol, noradrenaline had no effect on the cellular cAMP content. The Cl- secretion was measured as the amiloride-insensitive short circuit current (ISC). Addition of… CONTINUE READING