Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats

@article{Thaakur2009EffectOA,
  title={Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats},
  author={Santhrani Thaakur and G. Himabindhu},
  journal={Journal of Neural Transmission},
  year={2009},
  volume={116},
  pages={807-814}
}
Haloperidol (HAL) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis. Tardive dyskinesia (TD) is a complex hyperkinetic syndrome consisting of choreiform and athetoid movements, which persists for months or years after withdrawal. Increased levels of thiobarbituric acid reactive products are found in the cerebrospinal fluid and plasma of patients treated with neuroleptics, especially those with movement disorders. Alpha lipoic acid (ALA), a natural metabolic… CONTINUE READING

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Alpha lipoic acid ( ALA ) , a natural metabolic antioxidant , is effective in both prevention and treatment of numerous types of neurological disorders .
Alpha lipoic acid ( ALA ) , a natural metabolic antioxidant , is effective in both prevention and treatment of numerous types of neurological disorders .
It is proposed to study the effect of ALA on TD induced by HAL and to correlate it with oxidative stress by studying total antioxidant status and lipid peroxidation ( LP ) .
Haloperidol ( HAL ) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis .
Alpha lipoic acid ( ALA ) , a natural metabolic antioxidant , is effective in both prevention and treatment of numerous types of neurological disorders .
Alpha lipoic acid ( ALA ) , a natural metabolic antioxidant , is effective in both prevention and treatment of numerous types of neurological disorders .
Haloperidol ( HAL ) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis .
Haloperidol ( HAL ) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis .
Haloperidol ( HAL ) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis .
Haloperidol ( HAL ) is a widely used neuroleptic drug for the treatment of acute and chronic psychosis .
It is proposed to study the effect of ALA on TD induced by HAL and to correlate it with oxidative stress by studying total antioxidant status and lipid peroxidation ( LP ) .
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