Effect of allergen-specific immunotherapy on CD4+ T cells.

  title={Effect of allergen-specific immunotherapy on CD4+ T cells.},
  author={Erik Wambre},
  journal={Current opinion in allergy and clinical immunology},
  volume={15 6},
PURPOSE OF REVIEW The aims of this review are to discuss the impact of chronic high-dose allergen exposure on allergen-specific CD4(+) T-cell subset during allergen-specific immunotherapy (AIT) and discuss recent advances supporting novel mechanisms for desensitization and tolerance induction during AIT. (Figure is included in full-text article.) RECENT FINDINGS New technologies for direct molecular and cellular analysis have now provided an unprecedented opportunity to compare the functions… CONTINUE READING
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