Effect of alcohol on urinary glycosaminoglycan and protein excretion in normal and diabetic mice.

@article{Ramamurthi1990EffectOA,
  title={Effect of alcohol on urinary glycosaminoglycan and protein excretion in normal and diabetic mice.},
  author={R. Ramamurthi and C. B. Leevy and A. Reddi},
  journal={Alcohol and alcoholism},
  year={1990},
  volume={25 1},
  pages={
          45-50
        }
}
The effect of alcohol on urinary glycosaminoglycan (GAG) and protein excretion was studied in one-month-old normal control C57BL/6J (CBL) and genetically diabetic (db/db) mice. Ethyl alcohol (4 g/kg) was given once a day by gavage for 58-64 days. Increased amounts of urinary total GAGs and protein were found in diabetic mice. Alcohol treatment increased urinary excretion of total GAGs, heparan sulfate and protein only in nondiabetic CBL but not in diabetic mice. Also, alcohol increased… Expand
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