Effect of aggressive prolonged diethylcarbamazine therapy on circulating antigen levels in bancroftian filariasis.


BACKGROUND Single dose diethylcarbamazine (DEC) as used in control programmes is effectively microfilaricidal for periods of up to a year or more but has incomplete ability to kill Wuchereria bancrofti adult parasites. These regimens can be effective in breaking transmission by suppression of circulating microfilariae available to mosquito vectors. Whether… (More)


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