Effect of age on therapeutic response and survival in advanced Hodgkin's disease.

@article{Peterson1982EffectOA,
  title={Effect of age on therapeutic response and survival in advanced Hodgkin's disease.},
  author={Bruce A. Peterson and Thomas F. Pajak and Michael R. Cooper and Nis I. Nissen and O J Glidewell and James F. Holland and Clara D. Bloomfield and A. J. Gottlieb},
  journal={Cancer treatment reports},
  year={1982},
  volume={66 4},
  pages={889-98}
}
Although age is a recognized prognostic factor in advanced Hodgkin's disease, there are few data concerning the use of combination chemotherapy in patients greater than 60 years. In two phase III trials of the Cancer and Leukemia Group B, 385 previously untreated patients with stage III or IV Hodgkin's disease received multidrug chemotherapy. All patients received a combination of either mechlorethamine or a nitrosourea, as well as a vinca alkaloid, procarbazine, and prednisone. Two hundred and… CONTINUE READING

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