Effect of age on the sildenafil impact on the histological and ultrastructure of the liver in male albino rat

  • Hagar A. Hashish
  • Published 2016
Background: Sildenafil is one of PDE-5(phospho-diestrase enzyme) inhibitors. It is used as an antihypertensive drug. Sildenafil is mainly metabolized in the liver, and there are cautions regarding the dose when prescribing sildenafil to children, and patients with hepatic impairment. Materials and method: 24 male albino rats (150-350gm weight) were used… CONTINUE READING