Effect of age on the secretory capacity of pig small intestine in vivo and in vitro.

@article{McEwan1990EffectOA,
  title={Effect of age on the secretory capacity of pig small intestine in vivo and in vitro.},
  author={Gordon T. A. McEwan and Birgitte M B Schousboe and Claus G Nielsen and Erik Skadhauge},
  journal={The American journal of physiology},
  year={1990},
  volume={259 3 Pt 1},
  pages={G474-80}
}
The effect of age on the secretory response of pig small intestine to in vivo challenge by cholera toxin (CT) was investigated. The small intestine of 14-day-old pigs was more sensitive to CT challenge than that of 14-wk-old animals. In the 14-day jejunum CT-induced fluid secretion was five times that observed in the 14-wk tissue. Similarly, the 14-day ileum produced a fourfold higher secretion than the 14-wk ileum, although the magnitude of ileal secretion was markedly lower than that observed… CONTINUE READING