Effect of age on metabolic tolerance and hepatomegaly following chronic ethanol administration.

@article{Britton1984EffectOA,
  title={Effect of age on metabolic tolerance and hepatomegaly following chronic ethanol administration.},
  author={Robert S. Britton and Luis A Videla and G Rachamin and Fumitaka Okuno and Yedy Israel},
  journal={Alcoholism, clinical and experimental research},
  year={1984},
  volume={8 6},
  pages={528-34}
}
Chronic consumption of ethanol often results in an increased rate of ethanol metabolism (metabolic tolerance) and in hepatomegaly. However, the extent of these changes is highly variable. We have found that these two phenomena are greatly influenced by age. We studied the effect of age on the development of metabolic tolerance and hepatomegaly and on the increase in hepatic oxygen consumption produced by chronic ethanol administration. The latter has been proposed to contribute to metabolic… CONTINUE READING