Effect of age on epidermal immune function.


Like other systems in the body, the immune system deteriorates with age. Age-related changes in epidermal immune function include morphologic and functional changes in Langerhans cells, decreased production and response to epidermal thymocyte-activating factor (ETAF), and altered allergic contact dermatitis. These may be primary age-related changes in epidermal immune function or may be secondary to aging of the organism. In either case, the age-related changes in epidermal immunity may contribute to the increased susceptibility to cutaneous infections and neoplasms with advancing age.


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@article{Sauder1986EffectOA, title={Effect of age on epidermal immune function.}, author={Daniel Nathan Sauder}, journal={Dermatologic clinics}, year={1986}, volume={4 3}, pages={447-54} }