Effect of age on antioxidants and molecular markers of oxidative damage in murine epidermis and dermis.

@article{LpezTorres1994EffectOA,
  title={Effect of age on antioxidants and molecular markers of oxidative damage in murine epidermis and dermis.},
  author={M L{\'o}pez-Torres and Yasuko Shindo and Lester Packer},
  journal={The Journal of investigative dermatology},
  year={1994},
  volume={102 4},
  pages={476-80}
}
This is the first study of antioxidants and oxidative-damage-related parameters in epidermis and dermis of the skin as a function of age. The four major antioxidant enzymes (catalase, superoxide dismutase, glutathione reductase, and glutathione peroxidase), hydrophilic and lipophilic antioxidants, and lipid hydroperoxides were assayed in both epidermis and dermis of young and old hairless mice. Catalase, superoxide dismutase, and glutathione reductase had similar activity levels in young and… CONTINUE READING

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