Effect of age and food restriction on alkaline protease activity in rat liver.

@article{Shibatani1996EffectOA,
  title={Effect of age and food restriction on alkaline protease activity in rat liver.},
  author={Takeji Shibatani and Walter F. Ward},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={1996},
  volume={51 2},
  pages={B175-8}
}
The effect of age and food restriction on the hepatic alkaline protease activity of 100,000 x g supernatant has been investigated using 7-, 16-, and 26-month-old Fischer 344 rats. The proteasome, a major component of alkaline protease activity, is activated by sodium dodecyl sulfate (SDS) and this property was exploited to gain insight into the effects of… CONTINUE READING